Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society · 2011
[Effective glucocorticoid treatment in a case of idiopathic fibrosing mediastinitis].
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Kato Go, Takahashi Koichiro, Abe Tomonori, Kakino Chiho, Matsuo Ayako, Kobayashi Naomi, Komiya Kazutoshi, Sueoka-Aragane Naoko, Hayashi Shinichiro
Аннотация
A 54-year-old man was admitted to Saga University hospital with dyspnea on effort and a sensation of pressure in the chest. Chest CT images showed a low-density mass in the mediastinum surrounding the carina and left hilus, causing narrowing of both the left pulmonary artery and left main bronchus. The pathological findings from a surgical biopsy showed markedly fibrotic tissue with lymphocytes and plasmacytes, and we diagnosed idiopathic fibrosing mediastinitis, stage II. Oral glucocorticoid treatment of 30 mg/day prednisolone reduced the mass and improved the narrowing of the left pulmonary artery and left main bronchus. The patient was given low-dosage glucocorticoids as maintenance treatment. Previous reports indicated that idiopathic fibrosing mediastinitis with severe tissue fibrosis is difficult to control with glucocorticoid monotherapy. Here, we report a case of idiopathic fibrosing mediastinitis that was effectively treated with glucocorticoids.