Peripheral and optic neuritis in a patient with hemoglobin SC disease during treatment of salmonella osteomyelitis with chloramphenicol.

Peripheral and optic neuritis developed in a girl with hemoglobin SC disease, during long-term high-dose treatment of Salmonella osteomyelitis with chloramphenicol. Although the neurotoxicity of this antibiotic is well documented, the child's pain was initially considered to be a form of sickle-cell dactylitis.