Frontiers in public health · 2026
The pathogen spectrum of influenza-like illness in Guilin, China, 2023-2024.
СтатьяНазвание и аннотация: Перевод в очереди
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Cao Jin, Long Hu, Tian Wenyan, Qu Yingli, Mei Guoyong, Du Haijun, Xia Zhiqiang, Liu Mi, Song Qinqin, Cai Ru, Han Jun
Аннотация
OBJECTIVE: To investigate the pathogen spectrum and epidemiological characteristics of influenza-like illness (ILI) in Guilin, China, from 2023 to 2024.
METHODS: Between October 2023 and October 2024, 400 pharyngeal swabs were collected weekly from ILI patients and 18 respiratory pathogens were detected using quantitative real-time PCR (qPCR). Pathogen spectrum and epidemiological characteristics were analyzed.
RESULTS: Of the 400 samples, the overall pathogen-positive rate was 74.0% (296/400). Among the detected pathogens, Influenza (Flu) was the main pathogen (44.0%, 176/400), followed by SARS-CoV-2 (12.3%, 49/400) and Mycoplasma pneumoniae (MP) (8.8%, 35/400). The detection rate is highest in the age group of 45-59 years old, reaching 91.7%. The detection rates for Flu, SARS-CoV-2, MP, HAdV, RSV, EV, and HPIV showed significant differences among age groups (p < 0.05). The peak period of positive detection rate was autumn and winter (Nov 2023-Mar 2024). Flu (H3N2 and IBV) dominated in autumn and winter, but was gradually replaced by SARS-CoV-2 and MP thereafter. By autumn 2024, SARS-CoV-2 and HRV were predominant. Co-infections were identified in 14.2% (42/296) of positive cases, with the combination of Flu and MP being the most common (19.0%).
CONCLUSION: During the study period, ILI in Guilin was primarily driven by Flu, which co-circulated with other pathogens including SARS-CoV-2 and MP, demonstrating distinct seasonal patterns and demographic distributions.
METHODS: Between October 2023 and October 2024, 400 pharyngeal swabs were collected weekly from ILI patients and 18 respiratory pathogens were detected using quantitative real-time PCR (qPCR). Pathogen spectrum and epidemiological characteristics were analyzed.
RESULTS: Of the 400 samples, the overall pathogen-positive rate was 74.0% (296/400). Among the detected pathogens, Influenza (Flu) was the main pathogen (44.0%, 176/400), followed by SARS-CoV-2 (12.3%, 49/400) and Mycoplasma pneumoniae (MP) (8.8%, 35/400). The detection rate is highest in the age group of 45-59 years old, reaching 91.7%. The detection rates for Flu, SARS-CoV-2, MP, HAdV, RSV, EV, and HPIV showed significant differences among age groups (p < 0.05). The peak period of positive detection rate was autumn and winter (Nov 2023-Mar 2024). Flu (H3N2 and IBV) dominated in autumn and winter, but was gradually replaced by SARS-CoV-2 and MP thereafter. By autumn 2024, SARS-CoV-2 and HRV were predominant. Co-infections were identified in 14.2% (42/296) of positive cases, with the combination of Flu and MP being the most common (19.0%).
CONCLUSION: During the study period, ILI in Guilin was primarily driven by Flu, which co-circulated with other pathogens including SARS-CoV-2 and MP, demonstrating distinct seasonal patterns and demographic distributions.