Secretory A immunoglobulin, total proteins and salivary flow in Recurrent Aphthous Ulceration.

UNLABELLED: Clinical and experimental study. Introduction. Of debatable etiology, Recurrent Aphthous Ulcerations (R.A.U), is most of the time considered an immunological deficiency.

AIM: The aim of this paper is to review the literature and clinical investigations regarding IgA-s, total proteins salivary concentration and basal salivary flow of patients with R.A.U. during activity and quiescence.

METHODOLOGY: Nephelometry was used to measure salivary IgA-s; Pyrogallol red was used for total salivary proteins and the gravimetrical analysis for salivary flow measurement.

RESULTS

Results demonstrated a significant increase in salivary IgA-s in active lesions in relation to quiescence. On the other hand, protein concentration rates were similar in both periods.

CONCLUSION

Salivary IgA-s can be used as a parameter to study the immune status of the oral mucosa.