Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 1994
The efficacy of the combination of l-moprolol and dipivefrin in reducing the intraocular pressure in primary open-angle glaucoma or in ocular hypertension.
Клиническое исследованиеКлиническое исследование II фазыСтатьяРандомизированное исследованиеНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Rossetti L, Barbieri P, Velati P, Bujtar E, Orzalesi N
Аннотация
BACKGROUND: In this double-blind prospective trial the efficacy of lowering the intraocular pressure of l-moprolol given alone and in combination with dipivefrin was tested.
METHODS: Twenty-seven patients with primary open-angle glaucoma or ocular hypertension were randomly assigned to receive twice-daily l-moprolol eye drops or dipivefrin eye drops for 4 weeks; in a second phase of the trial, the combination of the two drugs was administered for 4 weeks.
RESULTS: The results of this study indicated that l-moprolol and dipivefrin had an equivalent effect in lowering the intraocular pressure. The association of the two drugs caused a further reduction of intraocular pressure which was significant only in the group previously treated with dipivefrin alone.
CONCLUSION: This trial demonstrated that the combination of l-moprolol and dipivefrin is an effective and safe treatment for elevated intraocular pressure.
METHODS: Twenty-seven patients with primary open-angle glaucoma or ocular hypertension were randomly assigned to receive twice-daily l-moprolol eye drops or dipivefrin eye drops for 4 weeks; in a second phase of the trial, the combination of the two drugs was administered for 4 weeks.
RESULTS: The results of this study indicated that l-moprolol and dipivefrin had an equivalent effect in lowering the intraocular pressure. The association of the two drugs caused a further reduction of intraocular pressure which was significant only in the group previously treated with dipivefrin alone.
CONCLUSION: This trial demonstrated that the combination of l-moprolol and dipivefrin is an effective and safe treatment for elevated intraocular pressure.