[Thoracic Aortic Thrombosis during Preoperative 5-Fluorouracil plus Cisplatin Therapy for Esophageal Cancer].

We report a case of thoracic aortic thrombosis that developed during preoperative 5-fluorouracil plus cisplatin(FP)therap y for esophageal cancer. Esophagectomy was performed after continued FP therapy along with anticoagulant therapy. The patient was an 80-year-old man diagnosed with thoracic esophageal cancer(Mt, cT3rN1M1a, cStage ⅢA). He was started on the FP regimen as neoadjuvant chemotherapy. Contrast-enhanced computed tomography(CT)after the first course of chemotherapy showed thoracic aortic thrombosis. FP chemotherapy was continued, and rivaroxaban was administered as an anticoagulant therapy. Preoperative CT revealed nearly complete thrombus resolution of the thrombus. The patient underwent a thoracoscopic esophagectomy with two-field lymph node dissection for esophageal cancer and was discharged after an uneventful postoperative course. There was no recurrence of aortic thrombosis.