Multicentric Reticulohistiocytosis: an Unknown Source of Embolic Stroke.

Multicentric reticulohistiocytosis (MRH) is a rare inflammatory disorder that presents with diverse systemic infiltrative manifestations. We report the first case of biopsy-proven MRH that presented with acute ischemic stroke in an embolic pattern. We discuss the clinical presentation, imaging findings, and diagnostic approach in our case. We also discuss the plausible etiology and mechanism of stroke associated with this rare disorder. MRH with its systemic involvement could present with neurological manifestations including ischemic infarcts.