Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2004
Postdialysis albumin: a better nutrition marker in pediatric hemodialysis patients?
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Wapensky Tanya, Alexander Steven R, Sarwal Minnie
Аннотация
BACKGROUND: Prehemodialysis serum albumin is considered an important indicator of nutritional status in pediatric hemodialysis (HD) patients. Study aim To determine whether serum albumin levels changed significantly from predialysis to postdialysis, and correlated with fluid changes over HD treatment.
METHODS: We prospectively measured pre-HD and post-HD albumin levels in 9 pediatric patients (ages 10 to 20 years; mean age, 16.3 years) on HD over an 8-month period. Changes in weight and albumin over 45 HD treatments were compared.
RESULTS: A total of 66.7% of pre-HD and 100% of post-HD albumin levels were within the normal range. Post-HD albumin was significantly higher than pre-HD in 42 of 45 observations (Mean, 4.7 +/- 0.39 g/dL versus 3.8 +/- 0.37; P <.0001). Delta albumin/treatment inversely correlated with weight loss (r = 0.741, P <.0001) and prescribed ultrafiltration rate (r = 0.764, P <.0001)
CONCLUSIONS: Serum albumin levels increase significantly postdialysis and inversely correlate with fluid removal. Pre-HD albumin level may not be a valid indicator of protein status because of the confounding effect of interdialytic weight gain, and may instead be a marker for fluid overload. Further studies are needed to assess the value of postdialysis albumin level as an indicator of nutritional status in pediatric HD patients.
METHODS: We prospectively measured pre-HD and post-HD albumin levels in 9 pediatric patients (ages 10 to 20 years; mean age, 16.3 years) on HD over an 8-month period. Changes in weight and albumin over 45 HD treatments were compared.
RESULTS: A total of 66.7% of pre-HD and 100% of post-HD albumin levels were within the normal range. Post-HD albumin was significantly higher than pre-HD in 42 of 45 observations (Mean, 4.7 +/- 0.39 g/dL versus 3.8 +/- 0.37; P <.0001). Delta albumin/treatment inversely correlated with weight loss (r = 0.741, P <.0001) and prescribed ultrafiltration rate (r = 0.764, P <.0001)
CONCLUSIONS: Serum albumin levels increase significantly postdialysis and inversely correlate with fluid removal. Pre-HD albumin level may not be a valid indicator of protein status because of the confounding effect of interdialytic weight gain, and may instead be a marker for fluid overload. Further studies are needed to assess the value of postdialysis albumin level as an indicator of nutritional status in pediatric HD patients.