International journal of dermatology · 1997
Toxic epidermal necrolysis--a retrospective study.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Criton S, Devi K, Sridevi P K, Asokan P U
Аннотация
BACKGROUND: Toxic epidermal necrolysis (TEN) is a severe, idiosyncratic, exfoliative disease of the skin and mucous membranes. The treatment of this condition is controversial. High-dose corticosteroid therapy has been the most commonly advocated treatment, but, more recently, this has changed to a no-steroid protocol. These conflicting treatments prompted us to evaluate retrospectively our protocol.
METHODS: The patients admitted to the hospital from 1989 to 1995 with a clinical diagnosis of TEN were included in the study. These patients were given systemic steroids, prophylactic antibiotic, and supportive measures.
RESULTS: The patients belonged to both sexes with an average age of 34 years. The average area of involvement was 85.62%. All the patients made an uneventful recovery without any evidence of sepsis.
CONCLUSIONS: Treatment with systemic steroids is useful in the management of TEN, and there is no need for a burn care center.
METHODS: The patients admitted to the hospital from 1989 to 1995 with a clinical diagnosis of TEN were included in the study. These patients were given systemic steroids, prophylactic antibiotic, and supportive measures.
RESULTS: The patients belonged to both sexes with an average age of 34 years. The average area of involvement was 85.62%. All the patients made an uneventful recovery without any evidence of sepsis.
CONCLUSIONS: Treatment with systemic steroids is useful in the management of TEN, and there is no need for a burn care center.