Prevalence of hypertriglyceridemia in adults and related cardiometabolic factors. SIMETAP-HTG study.
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Ruiz-García Antonio, Arranz-Martínez Ezequiel, López-Uriarte Beatriz, Rivera-Teijido Montserrat, Palacios-Martínez David, Dávila-Blázquez Gema M, Rosillo-González Antonio, González-Posada Delgado José Antonio, Mariño-Suárez José Enrique, Revilla-Pascual Enrique, Quintana-Gómez José Luis, Íscar-Valenzuela Ignacio, Alonso-Roca Rafael, Javierre-Miranda Ana Pilar, Escrivá-Ferrairó Rosa Ana, Tello-Meco Isabel, Ibarra-Sánchez Ana María, Gutiérrez Sánchez M Isabel, Iglesias Quintana Juan Ramón, Hernández-Beltrán M Inmaculada, Pérez Fernández Montserrat, Barrios-Rueda Elena, Pérez Muñoz Raúl, Prieto Marcos Miguel, Delgado Rodríguez Santiago, Pleite Raposo Raquel, Rodríguez-Cabanillas Rafael, Morales-Chico M Rosario, Fernández-Pacheco Vila Diana, Remón-Pérez Beatriz, Del Villar Redondo M Jesús, Reguillo-Díaz Joaquina, Aguilera Reija Paloma, Rodríguez Rodríguez Ana Olga, Gómez-Fernández Ofelia, Antón-Sanz M Del Carmen, Sánchez-Calso Antonio, Doria-Carlin Norma Alejandra, Frías-Vargas Manuel J, en representación del Grupo de Investigación del Estudio SIMETAP
Аннотация
METHODS: Cross-sectional observational study conducted in Primary Care, with 6,588 adult study subjects, randomly selected on base-population. Patients had HTG if the triglyceride level was≥150mg/dL (≥1.7mmol/L), or were on lipid-lowering therapy to lower triglyceride. Associations were assessed by univariate and multivariate analysis, and crude and sex- and age-adjusted prevalence rates were determined.
RESULTS: The arithmetic and geometric means of triglyceride levels were respectively 120.5 and 104.2mg/dL in global population, 135.7 and 116.0mg/dL in men, and 108.6 and 95.7mg/dL in women. The crude HTG prevalence rates were 29.6% in global population, 36.9% in men and 23.8% in women. The sex- and age-adjusted HTG prevalence rates were 27.0% in global population, 34.6% in men and 21.4% in women. The independent variables that were most associated with HTG were hypercholesterolemia (OR: 4.6), low HDL-C (OR: 4.1), hepatic steatosis (OR: 2.8), diabetes (OR: 2.0), and obesity (OR: 1.9).
CONCLUSIONS: The means of triglyceride levels and HTG prevalence rates are intermediate between those of other national and international studies. A fifth of the female adult population and more than a third of the male population had HTG. The independent factors associated with HTG were hypercholesterolemia and low HDL-C, and the cardiometabolic variables diabetes, hepatic steatosis and obesity.