Journal of neuroscience methods · 2014
BOOST: a supervised approach for multiple sclerosis lesion segmentation.
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Cabezas Mariano, Oliver Arnau, Valverde Sergi, Beltran Brigitte, Freixenet Jordi, Vilanova Joan C, Ramió-Torrentà Lluís, Rovira Alex, Lladó Xavier
Аннотация
BACKGROUND: Automatic multiple sclerosis lesion segmentation is a challenging task. An extensive analysis of the most recent techniques indicates an improvement of the results obtained when using prior knowledge and contextual information.
NEW METHOD: We present BOOST, a knowledge-based approach to automatically segment multiple sclerosis lesions through a voxel by voxel classification. We used the Gentleboost classifier and a set of features, including contextual features, registered atlas probability maps and an outlier map.
RESULTS: Results are computed on a set of 45 cases from three different hospitals (15 of each), obtaining a moderate agreement between the manual annotations and the automatically segmented results.
COMPARISON WITH EXISTING METHOD(S): We quantitatively compared our results with three public state-of-the-art approaches obtaining competitive results and a better overlap with manual annotations. Our approach tends to better segment those cases with high lesion load, while cases with small lesion load are more difficult to accurately segment.
CONCLUSIONS: We believe BOOST has potential applicability in the clinical practice, although it should be improved in those cases with small lesion load.
NEW METHOD: We present BOOST, a knowledge-based approach to automatically segment multiple sclerosis lesions through a voxel by voxel classification. We used the Gentleboost classifier and a set of features, including contextual features, registered atlas probability maps and an outlier map.
RESULTS: Results are computed on a set of 45 cases from three different hospitals (15 of each), obtaining a moderate agreement between the manual annotations and the automatically segmented results.
COMPARISON WITH EXISTING METHOD(S): We quantitatively compared our results with three public state-of-the-art approaches obtaining competitive results and a better overlap with manual annotations. Our approach tends to better segment those cases with high lesion load, while cases with small lesion load are more difficult to accurately segment.
CONCLUSIONS: We believe BOOST has potential applicability in the clinical practice, although it should be improved in those cases with small lesion load.