MedElevator
Войти в исследования International journal of pediatric otorhinolaryngology · 2025
Pediatric acute mastoiditis: A comparison of patients with and without intracranial complications.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Laryea Richmond, Zhang Wynne, Glaun Mica, Lee Jae Eun, Nguyen Justin Dat, Sitton Matthew S, Lambert Elton M
Аннотация
OBJECTIVE: To assess pediatric patients presenting with acute mastoiditis with and without intracranial complications (ICC) METHODS: A case series with retrospective review was performed on pediatric patients who presented to a pediatric tertiary care center with the diagnosis of mastoiditis from 2012 to 2020. All patients had a documented microbiology culture. The main factors compared among patients were bacteria isolated from cultures, antibiotic resistance, and occurrence of intracranial complications of mastoiditis.
RESULTS: 298 patients with mastoiditis were included in this study with an average age of 8.6 years (SD = 4.45). 41 of those patients presented with at least one intracranial complication (ICC) with the most common being epidural abscess (51 %). 143 (48 %) of patients had a history of acute otitis media prior to presentation, and thirty-eight patients (13 %) had a history of chronic otitis media prior to presentation. Patients with a history of acute otitis media were less likely to develop ICC compared to patients without a history of otologic infections OR: 0.49 (95 % CI = 0.24-0.99), p = 0.047. Patients with history of chronic otitis media were less likely to develop ICC compared to patients with no history of otologic infections OR: 0.20 (95 % CI = 0.04-0.90), p = 0.036. Patients with antibiotic use were more likely to develop ICC compared to antibiotic naïve patients OR: 2.64 (95 % CI = 1.31-5.32) p = 0.006. There was also no significant effect of patient sex, and ethnicity in the development of ICC.
CONCLUSION: The occurrence of intracranial complications from mastoiditis are noted to be higher in patients with no history of otologic infections. Additionally, the occurrence of ICC is noted to be higher among patients with prior antibiotic use.
LEVEL OF EVIDENCE: level 4 LEVEL OF EVIDENCE: level 4.
RESULTS: 298 patients with mastoiditis were included in this study with an average age of 8.6 years (SD = 4.45). 41 of those patients presented with at least one intracranial complication (ICC) with the most common being epidural abscess (51 %). 143 (48 %) of patients had a history of acute otitis media prior to presentation, and thirty-eight patients (13 %) had a history of chronic otitis media prior to presentation. Patients with a history of acute otitis media were less likely to develop ICC compared to patients without a history of otologic infections OR: 0.49 (95 % CI = 0.24-0.99), p = 0.047. Patients with history of chronic otitis media were less likely to develop ICC compared to patients with no history of otologic infections OR: 0.20 (95 % CI = 0.04-0.90), p = 0.036. Patients with antibiotic use were more likely to develop ICC compared to antibiotic naïve patients OR: 2.64 (95 % CI = 1.31-5.32) p = 0.006. There was also no significant effect of patient sex, and ethnicity in the development of ICC.
CONCLUSION: The occurrence of intracranial complications from mastoiditis are noted to be higher in patients with no history of otologic infections. Additionally, the occurrence of ICC is noted to be higher among patients with prior antibiotic use.
LEVEL OF EVIDENCE: level 4 LEVEL OF EVIDENCE: level 4.