Emerging infectious diseases · 2006
Severe community-acquired pneumonia due to Staphylococcus aureus, 2003-04 influenza season.
СтатьяНазвание и аннотация: Перевод в очереди
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Hageman Jeffrey C, Uyeki Timothy M, Francis John S, Jernigan Daniel B, Wheeler J Gary, Bridges Carolyn B, Barenkamp Stephen J, Sievert Dawn M, Srinivasan Arjun, Doherty Meg C, McDougal Linda K, Killgore George E, Lopatin Uri A, Coffman Rebecca, MacDonald J Kathryn, McAllister Sigrid K, Fosheim Gregory E, Patel Jean B, McDonald L Clifford
Аннотация
During the 2003-04 influenza season, 17 cases of Staphylococcus aureus community-acquired pneumonia (CAP) were reported from 9 states; 15 (88%) were associated with methicillin-resistant S. aureus (MRSA). The median age of patients was 21 years; 5 (29%) had underlying diseases, and 4 (24%) had risk factors for MRSA. Twelve (71%) had laboratory evidence of influenza virus infection. All but 1 patient, who died on arrival, were hospitalized. Death occurred in 5 (4 with MRSA). S. aureus isolates were available from 13 (76%) patients (11 MRSA). Toxin genes were detected in all isolates; 11 (85%) had only genes for Panton-Valentine leukocidin. All isolates had community-associated pulsed-field gel electrophoresis patterns; all MRSA isolates had the staphylococcal cassette chromosome mec type IVa. In communities with a high prevalence of MRSA, empiric therapy of severe CAP during periods of high influenza activity should include consideration for MRSA.
Предметные рубрики MeSH
AdolescentAdultChildChild, PreschoolCommunity-Acquired InfectionsDNA, BacterialElectrophoresis, Gel, Pulsed-FieldFemaleGenotypeHumansInfantInfluenza, HumanMaleMethicillin ResistanceMicrobial Sensitivity TestsMiddle AgedOrthomyxoviridaePneumonia, BacterialStaphylococcal InfectionsStaphylococcus aureus