MMWR. Morbidity and mortality weekly report · 2025

Pediatric Influenza-Associated Encephalopathy and Acute Necrotizing Encephalopathy - United States, 2024-25 Influenza Season.

СтатьяНазвание и аннотация: Перевод в очереди

Обработка статьи · этапы, ошибки и управление

Загрузка состояния…

История · было → стало

Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.

Fazal Amara, Harker Elizabeth J, Neelam Varsha, Olson Samantha M, Rolfes Melissa A, Reinhart Katie, Kniss Krista, Frutos Aaron, Leonard Jerome, Reed Carrie, Dugan Vivien G, Safi Haytham, Dulski Theresa M, Stanley-Downs Adrianna, Bhatti Aaliya, Armistead Isaac, Rao Suchitra, Torres-Diaz Carola, Thomas Ashlin, Weigel Andy, Patten Michael, Sinner Mallory, Nims Dawn, Mattingly Crystal, Gosack Valerie, Voris Amy, Redkey Jaime, Scaggs Huang Felicia A, DeCesaris Danielle, Tuggle Carrie, Betters Kristina A, Hand Julie, Krueger Anna, Potter Dina Z, Kim Curi, Park Rachel, Hong Sue, Edelman Hannah E, Kim Sue, Henderson Justin, McMahon Melissa, Sanders Jeffrey, Hunstad David A, Doran Emma L, Harbi Khalil, Julian Derek, Ball Hannah, Dreisig John, Thomas Deepam, Faybusovich Justin, Shaw Yomei P, Eisenberg Nancy, Chaturvedi Richa, Faulstich Ashleigh, Wester Rachel E, Gowie Donna L, Fisher Nicholas, Sutton Melissa, Boktor Sameh W, Long Jonah M, Marshall Patricia, Berns Abby L, McAda Lindsey, Winders Sarah, Gomez Pinedo Pamela, Murray Jade, Westbrook Ta'Kindra, Unutzer Anna, Lindquist Scott, Haupt Thomas E, Baum Kaylyn, Wilson-Murphy Molly, Glaser Carol, Harriman Kathleen, Antoon James W, Van Haren Keith P, Randolph Adrienne G, Silverman Andrew, de St Maurice Annabelle, Ellington Sascha, Uyeki Timothy M, Garg Shikha, CDC Influenza-Associated Encephalopathy Collaborators

Аннотация

In January 2025, CDC received several reports of deaths among children aged <18 years with a severe form of influenza-associated encephalopathy (IAE) termed acute necrotizing encephalopathy (ANE). Because no national surveillance for IAE currently exists, CDC requested notification of U.S. pediatric IAE cases from clinicians and health departments during the 2024-25 influenza season, a high-severity season with a record number of pediatric influenza-associated deaths. Among 192 reports of suspected IAE submitted to CDC, 109 (57%) were categorized as IAE, 37 (34%) of which were subcategorized as ANE, and 72 (66%) as other IAE; 82 reports did not meet IAE criteria and were categorized as other influenza-associated neurologic disease. The median age of children with IAE was 5 years and 55% were previously healthy, 74% were admitted to an intensive care unit, and 19% died; 41% of children with ANE died. Only 16% of children with IAE who were vaccination-eligible had received the 2024-25 influenza vaccine. Health care providers should consider IAE in children with encephalopathy or altered level of consciousness and a recent or current febrile illness when influenza viruses are circulating. Annual influenza vaccination is recommended for all children aged ≥6 months to prevent influenza and associated complications, potentially including severe neurologic disease such as IAE and ANE.

Предметные рубрики MeSH

United States Leukoencephalitis, Acute Hemorrhagic Influenza, Human Seasons Brain Diseases Population Surveillance Influenza Vaccines Vaccination Coverage Humans Male Female Infant, Newborn Infant Child, Preschool Child Adolescent Incidence

Pediatric Influenza-Associated Encephalopathy and Acute Necrotizing Encephalopathy - United States, 2024-25 Influenza Season.

Ошибки и ограничения

Аннотация

Предметные рубрики MeSH