Age and ageing · 2010
Predictors of long-term survival in nonagenarians: the NonaSantfeliu study.
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Formiga Francesc, Ferrer Assumpta, Chivite David, Rubio-Rivas Manuel, Cuerpo Sandra, Pujol Ramón
Аннотация
BACKGROUND: few studies have prospectively evaluated long-term predictors of mortality in nonagenarians.
OBJECTIVE: to determine predictors of death in a nonagenarian cohort after 5 years of follow-up.
DESIGN: a prospective community-based study.
SETTING: a community-based study.
SUBJECTS: one hundred and eighty-six nonagenarians both living in the community and institutionalised.
METHODS: functional status was determined by the Lawton-Brody and Barthel Indexes (BI) and cognition by the Spanish version of the mental state examination (MEC). The Charlson Index was used to measure comorbidity. Nutritional status was evaluated by the short version of the Mini-Nutritional Assessment questionnaire.
RESULTS: mortality after 5 years was 75.53%. Patients who did not survive were significantly older, with lower cognitive and functional performance, with diminished visual acuity, higher comorbidity, high risk of malnutrition, higher number of drugs taken and a higher percentage of patients with the diagnosis of dyslipidaemia, heart failure or previous stroke. Cox regression analysis, identified the Charlson Index (hazard ratio 1.23, 95% CI 1.09-1.37) and MEC (hazard ratio 0.98, 95% CI 0.97-0.99) as independent predictors of mortality after 5 years.
CONCLUSIONS: better cognitive status and lesser comorbidity at baseline are the best predictors to identify which nonagenarians survived after a 5-year follow-up period.
OBJECTIVE: to determine predictors of death in a nonagenarian cohort after 5 years of follow-up.
DESIGN: a prospective community-based study.
SETTING: a community-based study.
SUBJECTS: one hundred and eighty-six nonagenarians both living in the community and institutionalised.
METHODS: functional status was determined by the Lawton-Brody and Barthel Indexes (BI) and cognition by the Spanish version of the mental state examination (MEC). The Charlson Index was used to measure comorbidity. Nutritional status was evaluated by the short version of the Mini-Nutritional Assessment questionnaire.
RESULTS: mortality after 5 years was 75.53%. Patients who did not survive were significantly older, with lower cognitive and functional performance, with diminished visual acuity, higher comorbidity, high risk of malnutrition, higher number of drugs taken and a higher percentage of patients with the diagnosis of dyslipidaemia, heart failure or previous stroke. Cox regression analysis, identified the Charlson Index (hazard ratio 1.23, 95% CI 1.09-1.37) and MEC (hazard ratio 0.98, 95% CI 0.97-0.99) as independent predictors of mortality after 5 years.
CONCLUSIONS: better cognitive status and lesser comorbidity at baseline are the best predictors to identify which nonagenarians survived after a 5-year follow-up period.