[Metabolic indices for the bone tissue organic base metabolism and its mineral metabolism in patients with scoliosis].

The biochemical findings secured in the examination of 55 pediatric patients presenting with a progressing form of scoliosis suggested to us abnormalities of metabolism in the osseous tissue organic base and of the mineral metabolism. Indices capable of reflecting in the most unbiassed fashion the osseous tissue metabolic states include Ca/Cr, Ca/fr OP, Ph/Cr, Ph/fr OP ratios. Collagen and mineral metabolic disturbances result in structural changes in the vertebral osseous tissue organic base that may have an important part in the development of scoliotic disease.