[Leptin and food status in gastropancreatoduodenal pathology].

The regulation of weight of a body--is an actual problem of modern medicine. The significant part of patients with pathology of gastro-intestinal tract suffers of an increasing weight of a body. In economically advanced countries, including Russia, on the average each third inhabitant has an increasing weight of a body. Last researches shows, that the adipose tissue is not only a place of storage of power stocks, but also analogue endocryne body. The most part of peptides, participating in regulation of food behaviour, in a place of primary development in adipose cells, has been named adipokines. It is possible to attribute to them leptin. The purpose of our research was specification of influence of leptin level on character of a pathology of gastro-pancreato-duodenal zone. Under our supervision there were patients with diseases of gastro-pancreato-duodenal zone: chronic pancreatitis, duodenal ulcer, gastroduodenitis. It was revealed most increasing value of leptin in the patients with combination of chronic pancreatitis and duodenal ulcer.