Nature communications · 2021
Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Githinji George, de Laurent Zaydah R, Mohammed Khadija Said, Omuoyo Donwilliams O, Macharia Peter M, Morobe John M, Otieno Edward, Kinyanjui Samson M, Agweyu Ambrose, Maitha Eric, Kitole Ben, Suleiman Thani, Mwakinangu Mohamed, Nyambu John, Otieno John, Salim Barke, Kasera Kadondi, Kiiru John, Aman Rashid, Barasa Edwine, Warimwe George, Bejon Philip, Tsofa Benjamin, Ochola-Oyier Lynette Isabella, Nokes D James, Agoti Charles N
Аннотация
Genomic surveillance of SARS-CoV-2 is important for understanding both the evolution and the patterns of local and global transmission. Here, we generated 311 SARS-CoV-2 genomes from samples collected in coastal Kenya between 17th March and 31st July 2020. We estimated multiple independent SARS-CoV-2 introductions into the region were primarily of European origin, although introductions could have come through neighbouring countries. Lineage B.1 accounted for 74% of sequenced cases. Lineages A, B and B.4 were detected in screened individuals at the Kenya-Tanzania border or returning travellers. Though multiple lineages were introduced into coastal Kenya following the initial confirmed case, none showed extensive local expansion other than lineage B.1. International points of entry were important conduits of SARS-CoV-2 importations into coastal Kenya and early public health responses prevented established transmission of some lineages. Undetected introductions through points of entry including imports from elsewhere in the country gave rise to the local epidemic at the Kenyan coast.