Journal of the American Dental Association (1939) · 2007
Tooth loss, dementia and neuropathology in the Nun study.
СтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Stein Pamela Sparks, Desrosiers Mark, Donegan Sara Jean, Yepes Juan F, Kryscio Richard J
Аннотация
BACKGROUND: Numerous studies have linked dementia to the subsequent deterioration of oral health. Few investigators, however, have examined oral disease as a potential risk factor in the development of dementia. The authors conducted a study to investigate a potential association between a history of oral disease and the development of dementia.
METHODS: Longitudinal dental records supplemented data collected from 10 annual cognitive assessments of 144 Milwaukee participants in the Nun Study, a longitudinal study of aging and Alzheimer disease, who were 75 to 98 years old. Neuropathologic findings at autopsy were available for 118 participants who died.
RESULTS: A low number of teeth increased the risk of higher prevalence and incidence of dementia.
CONCLUSION: Participants with the fewest teeth had the highest risk of prevalence and incidence of dementia.
CLINICAL IMPLICATIONS: Edentulism or very few (one to nine) teeth may be predictors of dementia late in life.
METHODS: Longitudinal dental records supplemented data collected from 10 annual cognitive assessments of 144 Milwaukee participants in the Nun Study, a longitudinal study of aging and Alzheimer disease, who were 75 to 98 years old. Neuropathologic findings at autopsy were available for 118 participants who died.
RESULTS: A low number of teeth increased the risk of higher prevalence and incidence of dementia.
CONCLUSION: Participants with the fewest teeth had the highest risk of prevalence and incidence of dementia.
CLINICAL IMPLICATIONS: Edentulism or very few (one to nine) teeth may be predictors of dementia late in life.