Medicine · 2018
Hydroa vacciniforme-like cutaneous T-cell lymphoma in a child: A case report.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Li Jingyi, Zan Yiheng, Liu Hongjie, Liu Hanmin, Chen Lina
Аннотация
RATIONALE: Hydroa vacciniforme (HV)-like T-cell lymphoma is a rare malignancy in childhood associated with Epstein-Barr virus infection.
PATIENT CONCERNS: A 6-year old girl presented with complaint of 3-year history of recurrent skin lesions, 3 months of fever accompanied by cough for 8 days.
DIAGNOSES: Skin biopsy revealed a HV-like lymphoma presentation and positive signals of EBER were detected by in situ hybridization. TCR-γ gene monoclonal rearrangement was present. A HV-like cutaneous T-cell lymphoma was diagnosed.
INTERVENTIONS: The girl was treated with cyclosporine and CHOP.
OUTCOMES: The girl's condition had been stable for 6 months.
LESSONS: Our case highlights the necessity for taking the HV-like lymphoma as a differential diagnosis especially when a patient manifests as recurrent skin lesions accompanied by systemic involvement.
PATIENT CONCERNS: A 6-year old girl presented with complaint of 3-year history of recurrent skin lesions, 3 months of fever accompanied by cough for 8 days.
DIAGNOSES: Skin biopsy revealed a HV-like lymphoma presentation and positive signals of EBER were detected by in situ hybridization. TCR-γ gene monoclonal rearrangement was present. A HV-like cutaneous T-cell lymphoma was diagnosed.
INTERVENTIONS: The girl was treated with cyclosporine and CHOP.
OUTCOMES: The girl's condition had been stable for 6 months.
LESSONS: Our case highlights the necessity for taking the HV-like lymphoma as a differential diagnosis especially when a patient manifests as recurrent skin lesions accompanied by systemic involvement.