Hepato-gastroenterology · 2008
Late onset portal vein thrombosis and its risk factors.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Kishi Yoji, Sugawara Yasuhiko, Matsui Yuichi, Akamatsu Nobuhisa, Makuuchi Masatoshi
Аннотация
BACKGROUND/AIMS: Portal vein thrombosis (PVT) after liver transplantation is a fatal complication. The risk factors for PVT after LDLT remain to be clarified.
METHODOLOGY: A total of 287 consecutive living donor liver transplantations have been performed. Some clinical parameters of the recipients with and without postoperative PVT were compared to analyze the risk factors for PVT.
RESULTS: A total of 20 recipients (7%) were complicated with PVT. Of these 20, 6 patients had late onset PVT (> or =3 months after LDLT). There were no significant risk factors for early onset PVT (<3 months after LDLT). In contrast, a venous conduit for interposition was a significant risk factor for late onset PVT (multivariate analysis, p=0.02).
CONCLUSIONS: Use of venous conduit for portal vein interposition might be limited for better results although longer term follow-up and further case accumulation are necessary for more definitive conclusions.
METHODOLOGY: A total of 287 consecutive living donor liver transplantations have been performed. Some clinical parameters of the recipients with and without postoperative PVT were compared to analyze the risk factors for PVT.
RESULTS: A total of 20 recipients (7%) were complicated with PVT. Of these 20, 6 patients had late onset PVT (> or =3 months after LDLT). There were no significant risk factors for early onset PVT (<3 months after LDLT). In contrast, a venous conduit for interposition was a significant risk factor for late onset PVT (multivariate analysis, p=0.02).
CONCLUSIONS: Use of venous conduit for portal vein interposition might be limited for better results although longer term follow-up and further case accumulation are necessary for more definitive conclusions.