Alcoholism, clinical and experimental research · 1996
Bulimia nervosa and substance dependence: association and family transmission.
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Kaye W H, Lilenfeld L R, Plotnicov K, Merikangas K R, Nagy L, Strober M, Bulik C M, Moss H, Greeno C G
Аннотация
Alcohol and drug use disorders are common among women with bulimia nervosa (BN) and their family members. However, it is not known whether there is a familial relationship between BN and substance use disorders. We compared 47 women with BN and 44 non-eating-disordered community control women, and their first-degree relatives (177 and 190, respectively). BN probands were stratified by the presence (43%) or absence (57%) of lifetime alcohol and/or drug dependence. The first-degree relatives of substance-dependent BN probands had significantly higher lifetime rates of alcohol/drug dependence (38%), compared with relatives of nonsubstance-dependent BN probands (10%) or relatives of community controls (18%). These data suggest that BN and substance dependence are transmitted independently in families.