Abnormalities of sensory processing and sensorimotor interactions in secondary dystonia: a neurophysiological study in two patients.

Experimental data suggest that abnormalities of sensory processing and sensorimotor integration may play a role in the genesis of symptoms in primary dystonia. We studied 2 patients with dystonia secondary to lesions in the somatosensory pathways. We documented sensorimotor alterations in these patients that strongly resemble those found in primary dystonia. Our data are consistent with the hypothesis that abnormalities in sensorimotor processing may contribute to the pathogenesis of dystonic conditions.