Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2013
Periodic limb movements in sleep contribute to further cardiac structure abnormalities in hemodialysis patients with restless legs syndrome.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Giannaki Christoforos D, Zigoulis Paris, Karatzaferi Christina, Hadjigeorgiou Georgios M, George Keith P, Gourgoulianis Konstantinos, Koutedakis Yiannis, Stefanidis Ioannis, Sakkas Giorgos K
Аннотация
STUDY OBJECTIVES: In hemodialysis (HD) patients, restless legs syndrome (RLS) and periodic limb movements in sleep (PLMS) constitute common sleep disorders. Recent findings indicate a role for PLMS as a risk factor in the development of new or the aggravation of existing cardiovascular disease. The aim of the current study was to investigate the association of PLMS with indices of cardiac morphology and function in HD patients with RLS as a potential pathway by which PLMS could alter cardiovascular risk.
METHODS: Based on PLMS diagnosis by an overnight polysomnographic evaluation, 19 stable HD-RLS patients were divided into the PLMS group (n = 10) and the non-PLMS group (n = 9). During the overnight assessment, nocturnal blood pressure (BP) indices were also assessed. Left ventricular (LV) dimensions were examined by M-mode echocardiography, whereas LV diastolic function was evaluated by conventional Doppler and tissue Doppler imaging the following day.
RESULTS: LV internal diameter in diastole was significantly increased in the PLMS group (4.96 ± 0.61 vs 4.19 ± 0.48 cm, p = 0.007), leading to a significantly increase in LV mass (202 ± 52 vs 150 ± 37 g, p = 0.026). In contrast, no between group differences were observed in diastolic function indices (p > 0.05).
CONCLUSIONS: These are the first data to associate severe PLMS with further LV structure abnormalities in HD patients with RLS.
METHODS: Based on PLMS diagnosis by an overnight polysomnographic evaluation, 19 stable HD-RLS patients were divided into the PLMS group (n = 10) and the non-PLMS group (n = 9). During the overnight assessment, nocturnal blood pressure (BP) indices were also assessed. Left ventricular (LV) dimensions were examined by M-mode echocardiography, whereas LV diastolic function was evaluated by conventional Doppler and tissue Doppler imaging the following day.
RESULTS: LV internal diameter in diastole was significantly increased in the PLMS group (4.96 ± 0.61 vs 4.19 ± 0.48 cm, p = 0.007), leading to a significantly increase in LV mass (202 ± 52 vs 150 ± 37 g, p = 0.026). In contrast, no between group differences were observed in diastolic function indices (p > 0.05).
CONCLUSIONS: These are the first data to associate severe PLMS with further LV structure abnormalities in HD patients with RLS.
Предметные рубрики MeSH
AdultAge DistributionAgedBlood Chemical AnalysisCardiovascular DiseasesCohort StudiesComorbidityConfidence IntervalsCross-Sectional StudiesEchocardiography, DopplerFemaleHumansHypertrophy, Left VentricularIncidenceMaleMiddle AgedNocturnal Myoclonus SyndromePolysomnographyPrognosisReference ValuesRenal DialysisRestless Legs SyndromeRisk AssessmentSeverity of Illness IndexSex DistributionSleep Wake DisordersSurvival Rate