Gan to kagaku ryoho. Cancer & chemotherapy · 2016
[A Patient with Colon Cancer Local Site Recurrence Who Experienced Difficulty Tolerating Intensive Chemotherapy Was Treated Effectively with sLV5FU2 Therapy].
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Yoshioka Shinichi, Fukunaga Mutsumi, Tokuyama Shinji, Honda Shoko, Yukimoto Ryohei, Saito Akina, Okada Kazuyuki, Konishi Ken, Ota Hideo, Yokoyama Shigekazu, Miki Hirofumi, Kobayashi Kenji
Аннотация
An 82-year-old man underwent anterior resection for rectal cancer in 2006. Local recurrence was diagnosed 5 years and 4 months after the operation. He could not undergo intensive chemotherapy because of his age and health status(a history of tubercular and pancytopenia due to chronic hepatitis C). sLV5FU2 chemotherapy was initiated. The CEA level decreased immediately after chemotherapy, and a complete response was observed on CT. After 18 courses, chemotherapy was discontinued. A complete response was detected for 1 year after the chemotherapy holiday began. For patients who experience difficulty tolerating intensive chemotherapy, good outcomes have been achieved even if relatively light regimens are used. For elderly patients or those with several complications, we suggest selecting a regimen based on the QOL.