[The allergenic effect of rubber accelerators tetramethyl thiuram disulfide (TMTD) and mercaptobenzothiazole (MBT)].

The eczematogenic effects of tetramethylthiuramidsulfid and of mercaptobenzothiazol were studied on the basis of an inquiry in establishments using TMTD and MBT, a frequency analysis of positive reactions of our standard series in 1971 and testing of various rubber articles on sensitized persons as well as animal experiments. The results indicate a wider use, a higher percentage of positive epicutaneous tests and also a higher sensitizing potency in the animal test of the TMTD as compared with MBT. MBT was removed from our standard series.