[D-Trp-6 gonadotropin analog releasing hormone (Decapeptyl-Depot)-- the drug of choice in central idiopathic precocious puberty].

The authors submit their experience with the treatment of idiopathic precocious central puberty in two girls with the GnRH analog (Decapeptyl-Depot, Ferring Co.). The drug was administered for one an a half and two years resp., 80 mg/kg once per month. Apart from the effect on gonadarche and thelarche the pubertal growth rate was reduced to a prepubertal level and the originally accelerated bone maturation was reduced.