Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2007
Transient hypoparathyroidism following thyroidectomy: a prospective study and multivariate analysis of 604 consecutive patients.
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Cavicchi Ottavio, Piccin Ottavio, Caliceti Umberto, De Cataldis Angelo, Pasquali Renato, Ceroni Alberto Rinaldi
Аннотация
OBJECTIVE: The purpose of this study was to identify the risk factors for postoperative transient hypoparathyroidism in a group of patients undergoing thyroid surgery.
STUDY DESIGN: A prospective study was conducted on 604 patients undergoing thyroid surgery.
SUBJECTS AND METHODS: Gender, final diagnosis, extent of resection, biology of pathology, intrathoracic involvement, surgery for recurrent multinodular goiter, and presence and number of parathyroid glands in a surgical specimen were analyzed as risk factors for postoperative transient hypoparathyroidism. The chi-square test and a logistic regression analysis were applied.
RESULTS: On logistic regression analysis, only the extent of surgery constituted an independent variable for transient hypoparathyroidism (P = 0.001).
CONCLUSION: The extent of surgery to central and/or lateral neck lymph nodes is responsible for a high rate of transient hypoparathyroidism owing to a high probability of unplanned parathyroidectomy or parathyroid gland devascularization.
STUDY DESIGN: A prospective study was conducted on 604 patients undergoing thyroid surgery.
SUBJECTS AND METHODS: Gender, final diagnosis, extent of resection, biology of pathology, intrathoracic involvement, surgery for recurrent multinodular goiter, and presence and number of parathyroid glands in a surgical specimen were analyzed as risk factors for postoperative transient hypoparathyroidism. The chi-square test and a logistic regression analysis were applied.
RESULTS: On logistic regression analysis, only the extent of surgery constituted an independent variable for transient hypoparathyroidism (P = 0.001).
CONCLUSION: The extent of surgery to central and/or lateral neck lymph nodes is responsible for a high rate of transient hypoparathyroidism owing to a high probability of unplanned parathyroidectomy or parathyroid gland devascularization.
Предметные рубрики MeSH
Adenocarcinoma, FollicularAdolescentAdultAgedAged, 80 and overCarcinoma, PapillaryChildFemaleFollow-Up StudiesGoiter, NodularGoiter, SubsternalGraves DiseaseHumansHypoparathyroidismMaleMiddle AgedNeck DissectionParathyroidectomyPostoperative ComplicationsProspective StudiesRecurrenceReoperationRisk FactorsThyroid NeoplasmsThyroidectomy