The effect of in-home cognitive training on functional performance of individuals with mild cognitive impairment and early-stage Alzheimer's disease.

This intervention study compared an in-home cognitive training program to life story interview in 68 individuals with mild cognitive impairment or early-stage Alzheimer's disease. Family caregivers participated in sessions and reinforced learning between sessions. Analyses of covariance controlling for baseline levels were conducted. In comparison with the life story group, participants in the cognitive training group demonstrated significant improvement in all face-name association measures, several of the money-related tasks, and one of two event-related memory tasks. There were no differences in language outcomes or caregiver ratings of functional tasks except shopping. Caregivers in the life story group reported higher perceived satisfaction from being a caregiver. Comparison with earlier studies suggests in-home training is modestly more effective than office-based intervention. Results suggest that improvements are related to specific training and do not generalize to other tasks. Focusing on tasks of critical significance to participant and caregiver is recommended.