Detection of early abnormalities in the mucopolysaccharidoses by the use of visual and brainstem auditory evoked potentials.

Flash visual evoked potentials (FVEPs) and brainstem auditory evoked potentials (BAEPs) were performed in 13 children (aged 3-17 years) affected by mucopolysaccharidoses (MPSs). FVEPs and BAEPs were abnormal in 6 and 9 patients, respectively. The presence of these abnormalities in most neurologically normal patients suggests that electrophysiological techniques provide a useful tool for detecting early abnormalities.