International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 1976
Liver and brain thiamin depletion and neurologic signs in pigeon athiaminosis.
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Ferrari G, Cappelli V, Cariani T
Аннотация
Blood pyruvate and free and phosphorylated thiamin contents of liver and brain were measured in pigeons during diatary thiamin deficiency. Neurologic signs (opisthotonus and ataxia) appeared in the course of thiamin deficiency or did not appear at all during the entire athiaminosis period. As compared to respective controls, which never exhibited any neurologic abnormalities in spite of thiamin deficiency, the symptomatic animals had a higher pyruvate level in blood and a significantly lower phosphorylated thiamin content in both liver and brain. A hypothesis on relationship between phosphorylated thiamin content of liver and brain and occurence of nervous symptoms was expressed.