Clinical imaging · 2018
Whole-brain volume alteration and its correlation with anxiety severity in patients with obsessive-compulsive disorder and generalized anxiety disorder.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kim Gwang-Won, Yoon Woong, Jeong Gwang-Woo
Аннотация
PURPOSE: To evaluate the differential gray matter (GM) and white matter volume alterations between healthy controls and patients with obsessive-compulsive disorder (OCD) and generalized anxiety disorder (GAD) using voxel-based morphometry (VBM).
METHOD: Patients with OCD and GAD, and healthy controls underwent MR.
RESULTS: Patients with GAD showed significantly decreased GM volume in the medial prefrontal cortex (mPFC) compared with patients with OCD (p < 0.001). The GM volumes of the mPFC in patients with GAD were negatively correlated with Hamilton Anxiety Rating Scales.
CONCLUSION: Our findings indicate that the mPFC volume abnormality may be associated with anxiety disorder in patients with GAD rather than OCD.
METHOD: Patients with OCD and GAD, and healthy controls underwent MR.
RESULTS: Patients with GAD showed significantly decreased GM volume in the medial prefrontal cortex (mPFC) compared with patients with OCD (p < 0.001). The GM volumes of the mPFC in patients with GAD were negatively correlated with Hamilton Anxiety Rating Scales.
CONCLUSION: Our findings indicate that the mPFC volume abnormality may be associated with anxiety disorder in patients with GAD rather than OCD.