Journal of dentistry · 2026
Managing dentine erosion with silver diamine fluoride: An in situ study.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Chawhuaveang Dhananthat, Lam Walter Yu Hang, Chan Alice Kit Ying, Chu Chun Hung, Yu Ollie Yiru
Аннотация
OBJECTIVES: To evaluate anti-erosive effect and associated color change (ΔE00) of 38% silver diamine fluoride (SDF) on human dentine.
METHODS: A crossover in situ study involving 15 volunteers was conducted. Participants wore an intra-oral appliance carrying four dentine blocks for three 14-day treatment phases, separated by a 7-day washout period. Three treatments included weekly application of 38% SDF (255,000 ppmAg and 44,800 ppmF, Group SDF), daily application of stannous chloride/amine fluoride/sodium fluoride (800 ppmSn and 500 ppmF, Group SNF), and daily application of deionized water (Group DW). Appliances with dentine blocks were exposed to citric acid (pH 3.2), five daily extraoral erosive challenges. Dentine blocks were assessed for percentage surface microhardness loss (%SMHL), dentine loss, salivary pellicle morphology, crystal characteristics, dentine surface morphology, elemental composition, and ΔE00 by a microhardness tester, optical profilometry, atomic force microscopy (AFM), X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), and spectrophotometry, respectively.
RESULTS: %SMHL of the experimental groups were SDF:23.3 ± 2.4, SNF:30.2 ± 2.0 and DW:42.4 ± 2.2 (SDF<SNF<DW; p < 0.001). Dentine loss (μm) were SDF:4.2 ± 1.1, SNF: 6.1 ± 1.4, and DW:10.5 ± 1.4 (SDF<SNF<DW; p < 0.001). AFM revealed a globular appearance of the pellicle on the surfaces of Groups SDF and SNF. XRD showed the formation of silver-containing compounds in Group SDF. SEM images showed dentinal tubular occlusion in Group SDF. EDS confirmed silver deposition in Group SDF. ΔE00: SDF 14.8 ± 2.4, SNF 8.1 ± 2.2, DW 4.8 ± 2.3 (SDF>SNF>DW; p < 0.001).
CONCLUSION: Weekly application of 38% SDF demonstrated significantly better anti-erosive protection but caused black staining on dentine surfaces.
CLINICAL SIGNIFICANCE: SDF with weekly application has been demonstrated to be effective in preventing dentine erosion, although dentine staining remains a clinical consideration.
METHODS: A crossover in situ study involving 15 volunteers was conducted. Participants wore an intra-oral appliance carrying four dentine blocks for three 14-day treatment phases, separated by a 7-day washout period. Three treatments included weekly application of 38% SDF (255,000 ppmAg and 44,800 ppmF, Group SDF), daily application of stannous chloride/amine fluoride/sodium fluoride (800 ppmSn and 500 ppmF, Group SNF), and daily application of deionized water (Group DW). Appliances with dentine blocks were exposed to citric acid (pH 3.2), five daily extraoral erosive challenges. Dentine blocks were assessed for percentage surface microhardness loss (%SMHL), dentine loss, salivary pellicle morphology, crystal characteristics, dentine surface morphology, elemental composition, and ΔE00 by a microhardness tester, optical profilometry, atomic force microscopy (AFM), X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), and spectrophotometry, respectively.
RESULTS: %SMHL of the experimental groups were SDF:23.3 ± 2.4, SNF:30.2 ± 2.0 and DW:42.4 ± 2.2 (SDF<SNF<DW; p < 0.001). Dentine loss (μm) were SDF:4.2 ± 1.1, SNF: 6.1 ± 1.4, and DW:10.5 ± 1.4 (SDF<SNF<DW; p < 0.001). AFM revealed a globular appearance of the pellicle on the surfaces of Groups SDF and SNF. XRD showed the formation of silver-containing compounds in Group SDF. SEM images showed dentinal tubular occlusion in Group SDF. EDS confirmed silver deposition in Group SDF. ΔE00: SDF 14.8 ± 2.4, SNF 8.1 ± 2.2, DW 4.8 ± 2.3 (SDF>SNF>DW; p < 0.001).
CONCLUSION: Weekly application of 38% SDF demonstrated significantly better anti-erosive protection but caused black staining on dentine surfaces.
CLINICAL SIGNIFICANCE: SDF with weekly application has been demonstrated to be effective in preventing dentine erosion, although dentine staining remains a clinical consideration.
Предметные рубрики MeSH
HumansDentinTooth ErosionQuaternary Ammonium CompoundsHardnessSilver CompoundsMicroscopy, Electron, ScanningSodium FluorideCross-Over StudiesMicroscopy, Atomic ForceDental PellicleSpectrometry, X-Ray EmissionAdultX-Ray DiffractionFluorides, TopicalTin CompoundsMaleCitric AcidYoung AdultFemaleTin FluoridesSurface PropertiesAminesFluoride TreatmentColorCrystallographyCrystallizationWaterCariostatic Agents