Journal of the American Geriatrics Society · 2011
Cognitive impairment predicts fatal incident stroke: findings from a national sample of older adults.
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Clarke Philippa J, Blount Vanessa, Colantonio Angela
Аннотация
OBJECTIVES: To investigate the effect of cognitive impairment on fatal and nonfatal incident stroke in older adults.
DESIGN: A large, national, prospective, population-based study of a representative cohort of older Canadians followed over a 10-year period.
SETTING: Secondary analyses were conducted using data from the Canadian Study of Health and Aging, a population-based study of older adults followed prospectively from 1991 to 2001.
PARTICIPANTS: Nine thousand four hundred fifty-one adults aged 65 and older who had not previously been diagnosed with stroke at baseline (in 1991).
MEASUREMENTS: In addition to known risk factors, the independent contribution of cognitive function (diagnosed in a clinical examination) was examined as a risk for stroke in older adults.
RESULTS: Multinomial logistic regression analyses showed that cognitive impairment was associated with twice the odds of fatal incident stroke, controlling for well-established risk factors.
CONCLUSION: This study provides further evidence for the need to consider cognitive function in relation to stroke risk in older populations.
DESIGN: A large, national, prospective, population-based study of a representative cohort of older Canadians followed over a 10-year period.
SETTING: Secondary analyses were conducted using data from the Canadian Study of Health and Aging, a population-based study of older adults followed prospectively from 1991 to 2001.
PARTICIPANTS: Nine thousand four hundred fifty-one adults aged 65 and older who had not previously been diagnosed with stroke at baseline (in 1991).
MEASUREMENTS: In addition to known risk factors, the independent contribution of cognitive function (diagnosed in a clinical examination) was examined as a risk for stroke in older adults.
RESULTS: Multinomial logistic regression analyses showed that cognitive impairment was associated with twice the odds of fatal incident stroke, controlling for well-established risk factors.
CONCLUSION: This study provides further evidence for the need to consider cognitive function in relation to stroke risk in older populations.