[The effect of prolonged injestion of paraffin oil in pigs: selective retention and interference with cholesterol metabolism].

Hydrocarbons administered to the pig as paraffin oil fix preferentially in the liver, and the existence of a selective filtration mechanism can be supposed. Moreover a significant increase of the level of squalene is observed in adipose tissue and liver; it could correspond to an inhibition of the cholesterol synthesis following vitamin A deficiency due to perturbation of intestinal absorption.