Ocular immunology and inflammation · 2025
Paediatric Ocular Sarcoidosis - Clinical Profiles from a Tertiary Eye Care Centre in South India.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Babu Kalpana, Padmapriya P G, Mooss Vidya
Аннотация
PURPOSE: We aim to look at the clinical profile in paediatric ocular sarcoidosis in a tertiary eye centre from South India.
METHODS: Retrospective study between 2012 and 2024.
RESULTS: A total of 29 cases of paediatric ocular sarcoidosis including 19 cases of late onset sarcoid and 10 cases of early onset sarcoid/Blau syndrome were retrieved from our medical database. There was no significant association with age and gender in both groups. Children with Blau syndrome were first presented to a rheumatologist and were associated with systemic manifestations than the late onset sarcoid group (p = 0.002). Bilaterality and granulomatous panuveitis were the most common presentations in both the groups. Corneal involvement (p = 0.001) and depigmented chorioretinal scars (p = 0.048) were significantly more common in the Blau syndrome group. The response was good in 79.2% with no inflammation at the time of the last follow-up. There was a significant improvement in the best corrected visual acuity at final follow-up in the late onset sarcoid group (p = 0.001).
CONCLUSIONS: Paediatric ocular sarcoidosis is underreported in India. This series highlights the clinical profiles in the two types of paediatric ocular sarcoidosis.
METHODS: Retrospective study between 2012 and 2024.
RESULTS: A total of 29 cases of paediatric ocular sarcoidosis including 19 cases of late onset sarcoid and 10 cases of early onset sarcoid/Blau syndrome were retrieved from our medical database. There was no significant association with age and gender in both groups. Children with Blau syndrome were first presented to a rheumatologist and were associated with systemic manifestations than the late onset sarcoid group (p = 0.002). Bilaterality and granulomatous panuveitis were the most common presentations in both the groups. Corneal involvement (p = 0.001) and depigmented chorioretinal scars (p = 0.048) were significantly more common in the Blau syndrome group. The response was good in 79.2% with no inflammation at the time of the last follow-up. There was a significant improvement in the best corrected visual acuity at final follow-up in the late onset sarcoid group (p = 0.001).
CONCLUSIONS: Paediatric ocular sarcoidosis is underreported in India. This series highlights the clinical profiles in the two types of paediatric ocular sarcoidosis.