Transplant infectious disease : an official journal of the Transplantation Society · 2020
Kinetics of torquetenovirus DNA load in a recent kidney transplant recipient with mild SARS-CoV-2 infection and a failed antibody response.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Querido Sara, Calça Rita, Weigert André, Francisco Diogo, Adragão Teresa, Ana Pessanha Maria, Gomes Perpétua, Rodrigues Luís, Figueira João M, Cardoso Conceição, Machado Domingos
Аннотация
Kidney transplant (KT) recipients are at an increased risk for severe COVID-19 because of their immunosuppressed state. A 42-year-old KT patient was diagnosed with COVID-19 three months after KT. Despite lymphopenia and several risk factors, he had a mild disease course. Nasopharyngeal real-time reverse transcriptase polymerase chain reaction for SARS-CoV-2 became negative 48 days after detection. SARS-CoV-2 IgG antibodies became negative after day 40. TTV DNA load increased with the onset COVID-19 and reduced after its resolution. This is the first report where TTV DNA load was measured during the course of COVID-19.
Предметные рубрики MeSH
AdultAntibodies, ViralCOVID-19COVID-19 Nucleic Acid TestingCOVID-19 Serological TestingComorbidityDNA Virus InfectionsDNA, ViralDiabetes MellitusGlucocorticoidsGraft RejectionHumansHypertensionImmunocompromised HostImmunoglobulin GImmunoglobulin MImmunosuppressive AgentsKidney TransplantationKineticsLymphopeniaMaleMycophenolic AcidObesityPrednisoloneSARS-CoV-2Severity of Illness IndexTacrolimusTorque teno virusViral Load