BJU international · 2012
The impact of sleep apnoea syndrome on nocturia according to age in men.
Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Kang Suk-Hoon, Yoon In-Young, Lee Sang Don, Kim Jeong-Whun
Аннотация
UNLABELLED: Study Type--Symptom prevalence (cohort) Level of Evidence 2b. What's known on the subject? and What does the study add? Sleep apnoea syndrome (SAS) can be a risk factor for nocturia, although whether the relationship between nocturia and SAS changes according to age remains to be addressed. SAS has a modest impact on nocturia frequency and the prevalence of pathological nocturia in young adults and middle-aged men. However, SAS may not be a risk factor for nocturia in the elderly, and age-related urinary diseases and voiding dysfunctions could over-ride the influence of SAS on nocturia in the elderly.
OBJECTIVE: • To assess the association between nocturia and sleep apnoea syndrome (SAS) according to age, as well as to determine the factors related to nocturia.
PATIENTS AND METHODS: • A total of 1757 men who had been referred to a sleep laboratory underwent polysomnography. • Nocturia frequency was assessed using a questionnaire, and pathological nocturia was defined as the need to void two or more times per night. • The Pittsburgh Sleep Quality Index (PSQI) and Beck Depression Inventory (BDI) were applied to all study subjects.
RESULTS: • Nocturia frequency was significantly correlated with age (r = 0.405, P < 0.001) and the apnoea-hypopnoea index (AHI) (r = 0.065, P < 0.01). • In those men aged <65 years, significant correlations were found between nocturic frequency and age, AHI, BDI and PSQI. • Multiple regression analysis showed that age (β = 0.303, P < 0.001), AHI (β = 0.107 P < 0.001) and benign prostatic hypertrophy (BPH; β = 0.069, P < 0.01) were associated with nocturia, and that the presence of pathological nocturia was predicted by BPH (odds ratio [OR], 2.77; P < 0.01), age (OR, 1.09; P < 0.001) and AHI (OR, 1.02; P < 0.001). • However, in men aged >65 years, nocturia frequency was significantly associated with BDI and PSQI, although no relationship was found between nocturia frequency and SAS parameters. • BPH was more frequently observed in elderly men with pathological nocturia than in those without pathological nocturia (OR, 2.18; P < 0.05).
CONCLUSIONS: • In the elderly, SAS may not be a risk factor for nocturia. • Age-related urinary diseases and voiding dysfunction may over-ride the influence of SAS.
OBJECTIVE: • To assess the association between nocturia and sleep apnoea syndrome (SAS) according to age, as well as to determine the factors related to nocturia.
PATIENTS AND METHODS: • A total of 1757 men who had been referred to a sleep laboratory underwent polysomnography. • Nocturia frequency was assessed using a questionnaire, and pathological nocturia was defined as the need to void two or more times per night. • The Pittsburgh Sleep Quality Index (PSQI) and Beck Depression Inventory (BDI) were applied to all study subjects.
RESULTS: • Nocturia frequency was significantly correlated with age (r = 0.405, P < 0.001) and the apnoea-hypopnoea index (AHI) (r = 0.065, P < 0.01). • In those men aged <65 years, significant correlations were found between nocturic frequency and age, AHI, BDI and PSQI. • Multiple regression analysis showed that age (β = 0.303, P < 0.001), AHI (β = 0.107 P < 0.001) and benign prostatic hypertrophy (BPH; β = 0.069, P < 0.01) were associated with nocturia, and that the presence of pathological nocturia was predicted by BPH (odds ratio [OR], 2.77; P < 0.01), age (OR, 1.09; P < 0.001) and AHI (OR, 1.02; P < 0.001). • However, in men aged >65 years, nocturia frequency was significantly associated with BDI and PSQI, although no relationship was found between nocturia frequency and SAS parameters. • BPH was more frequently observed in elderly men with pathological nocturia than in those without pathological nocturia (OR, 2.18; P < 0.05).
CONCLUSIONS: • In the elderly, SAS may not be a risk factor for nocturia. • Age-related urinary diseases and voiding dysfunction may over-ride the influence of SAS.