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PURPOSE: In 2018, the Isère department implemented a promotional campaign for HPV vaccination called "StopHV." Our article aims to examine the impact of this campaign on the evolution of HPV vaccination coverage in Isère.

METHOD: The research study adopted a mixed-methods approach, incorporating qualitative components (focus groups) to contextualize quantitative results (surveys conducted in various secondary schools across the department), combined with vaccination coverage data.

RESULTS

In Isère, vaccination coverage for one dose of the HPV vaccine increased from 21.7% in 2017 to 49.7% in 2022 (Santé Publique France). In 2022-2023, the main reason for non-vaccination remained fear of side effects, followed by lack of time. Among the survey participants, 95% reported having consulted their general practitioner for information about vaccination. A significant association was found between girls' vaccination status and parents' socio-professional category, as well as between Priority Education Network (REP) status and awareness of the HPV vaccine.

DISCUSSION: Our study suggests that the StopHPV campaign was effective in achieving its goal of doubling HPV vaccination coverage by 2022. Our evaluation highlights the importance of maintaining training for general practitioners on HPV vaccination and the relevance of implementing school-based vaccination campaigns. It also appears essential to address socio-cultural inequalities by delivering targeted messages in schools belonging to Priority Education Networks.