Incidence of Paneth cells in colorectal adenomas of Japanese descendants in Hawaii.

The main purpose of the present study was to demonstrate the incidence of Paneth cells in colorectal tubular adenomas of Japanese descendants in Hawaii. Paneth cells were found in 73 of 322 adenomas (22.7%) of Japanese descendants in Hawaii. The incidence of Paneth cells in adenomas located from the caecum to the transverse colon was significantly higher than that of adenomas from the descending colon to the rectum. The same trend of a higher incidence of Paneth cells in adenomas from the caecum to the transverse colon was observed in Japanese descendants and Caucasian residents in Hawaii and in native Japanese. The incidence of Paneth cells in adenomas of Japanese descendants in Hawaii was higher than that of native Japanese, and also that of Caucasian residents was higher than that of native Japanese.