25OH Vitamin D Is No Associated with Muscle Function Loss in Adults and Elderly Patients Undergoing Hemodialysis.

OBJECTIVES

In patients with chronic kidney disease, sarcopenia is associated with dialysis treatment, accelerated protein catabolism, and high energy demand. Thus, this study aimed to assess the association between 25-OH vitamin D concentrations and muscle function in patients undergoing hemodialysis.

DESIGN

A cross-sectional study.

SETTING

Performed in a hemodialysis clinic.

PARTICIPANTS

79 adult and elderly patients undergoing hemodialysis.

MEASUREMENTS: The sample was divided according to the SARC-F definition, being 55 patients allocated in the SARC-F <4 group and 24 in the SARC-F ≥4 group. Normal 25-OH vitamin D concentrations was considered when ≥30 ng/dL.

RESULTS

Vitamin D concentrations and number of patients with low or normal muscle function did not differ between the groups. There was no correlation between SARC-F and 25-OH vitamin D levels (r: -0.09, p=0.42).

CONCLUSIONS

25-OH vitamin D has no association with muscle function loss in adults and elderly patients undergoing hemodialysis.