Tubuloreticular structures in pyridoxine deficiency.

Electron microscopic studies on renal tissue obtained from animals subjected to pyridoxine deficiency have revealed the presence of round and/or tubular bodies in the cytoplasm of endothelial cells of the glomeruli. The bodies generally occur as aggregates in association with the endoplasmic reticulum. Along with the round forms other profiles are also observed. It is believed that they represent one of the many images of a system of undulating tubules. Since these bodies occur irrespective of the presence of virus particles in the tissue under study it is concluded that they are not viral in nature.