The journal of evidence-based dental practice · 2020
Caries Status and Salivary Alterations of Type-1 Diabetes Mellitus in Children and Adolescents: A Systematic Review and Meta-analysis.
СтатьяМетаанализПоддержка исследования: вне правительства СШАСистематический обзорНазвание и аннотация: Перевод пока не подготовлен
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Liu Ting, Wei Yuan, Zhu Yanan, Yang Weidong
Аннотация
INTRODUCTION: The association between dental caries, salivary alterations, and type-1 diabetes mellitus (D1TM) remains inconclusive in children and adolescents. This systematic review evaluated the caries status and salivary alterations of children and adolescents suffering from D1TM.
METHODS: Meta-analysis searched from 5 electronic databases was performed considering the decay-missing-filled teeth (DMFT), decay-missing-filled surfaces, and decay-missing-filled primary teeth (dmft) index for caries and the stimulated flow rate, unstimulated flow rate, and buffering capacity for salivary alterations. Quality assessments were performed using the Healthcare Research and Quality Agency.
RESULTS: Eleven studies satisfied the eligibility criteria. The meta-analysis revealed that DMF(T) (0.61; 95% confidence interval [CI], 0.14-1.08, P = .01) and dmft (-0.43; 95% CI, -0.71 to -0.15, P = .002) were significantly higher in D1TM group than the non-D1TM group. Stimulated flow rate (-0.40; 95% CI, -0.57 to -0.23, P < .00001) was significantly lower in D1TM group than in the non-D1TM group. No significant differences in decay-missing-filled surfaces and the buffering capacity were observed between the D1TM and the non-D1TM groups.
CONCLUSIONS: The level of DMF(T) and dmft was higher in children/adolescents with D1TM than that with non-D1TM, and the salivary flow could be considered decreased with D1TM. The strength of the evidence of the studies analyzed, however, was deemed to be moderate and low.
METHODS: Meta-analysis searched from 5 electronic databases was performed considering the decay-missing-filled teeth (DMFT), decay-missing-filled surfaces, and decay-missing-filled primary teeth (dmft) index for caries and the stimulated flow rate, unstimulated flow rate, and buffering capacity for salivary alterations. Quality assessments were performed using the Healthcare Research and Quality Agency.
RESULTS: Eleven studies satisfied the eligibility criteria. The meta-analysis revealed that DMF(T) (0.61; 95% confidence interval [CI], 0.14-1.08, P = .01) and dmft (-0.43; 95% CI, -0.71 to -0.15, P = .002) were significantly higher in D1TM group than the non-D1TM group. Stimulated flow rate (-0.40; 95% CI, -0.57 to -0.23, P < .00001) was significantly lower in D1TM group than in the non-D1TM group. No significant differences in decay-missing-filled surfaces and the buffering capacity were observed between the D1TM and the non-D1TM groups.
CONCLUSIONS: The level of DMF(T) and dmft was higher in children/adolescents with D1TM than that with non-D1TM, and the salivary flow could be considered decreased with D1TM. The strength of the evidence of the studies analyzed, however, was deemed to be moderate and low.