Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2014
[Chronobiological characteristics of stroke and poststroke cognitive impairment].
Контролируемое клиническое исследованиеАннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kulesh A A, Lapaeva T V, Shestakov V V
Аннотация
OBJECTIVE: To study chronobiological characteristics of ischemic stroke (II) and post stroke cognitive impairment (CI).
MATERIAL AND METHODS: We examined 80 patients with acute ischemic stroke. The cognitive status, sleep quality, chronobiological parameters and night urinary level of 6-sulfatoxymelatonin were assessed. The clinical observation of the efficacy of melaxen treatment in intensive care unit was performed.
RESULTS: The results of the study indicate the significance of social and environmental factors which determine the sleep-wake behavior in the development of pineal dysfunction. The pineal dysfunction probably underlies the development of stroke and accompanied neurodegenerative process.
CONCLUSION: The use of melaxen in hyperacute stroke was associated with better recovery of circadian rhythms and rehabilitation results.
MATERIAL AND METHODS: We examined 80 patients with acute ischemic stroke. The cognitive status, sleep quality, chronobiological parameters and night urinary level of 6-sulfatoxymelatonin were assessed. The clinical observation of the efficacy of melaxen treatment in intensive care unit was performed.
RESULTS: The results of the study indicate the significance of social and environmental factors which determine the sleep-wake behavior in the development of pineal dysfunction. The pineal dysfunction probably underlies the development of stroke and accompanied neurodegenerative process.
CONCLUSION: The use of melaxen in hyperacute stroke was associated with better recovery of circadian rhythms and rehabilitation results.