Journal of clinical periodontology · 2009
Clinical evaluation of a new collagen matrix (Mucograft prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial.
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Sanz Mariano, Lorenzo Ramón, Aranda Juan J, Martin Conchita, Orsini Marco
Аннотация
AIM: The aim of this study was to test a new collagen matrix (CM) aimed to increase keratinized gingiva/mucosa when compared with the free connective tissue graft (CTG).
MATERIAL AND METHODS: This randomized longitudinal parallel controlled clinical trial studied 20 patients with at least one location with minimal keratinized tissue (<or=1 mm).
MAIN OUTCOME MEASURE: The 6-month width of keratinized tissue. As secondary outcomes, the aesthetic outlook, the maintenance of periodontal health and the patient morbidity were assessed pre-operatively at 1, 3 and 6 months.
RESULTS: At 6 months, the CTG attained a mean width of keratinized tissue of 2.6 (0.9) mm, while the CM was 2.5 (0.9) mm, these differences being insignificant. In both groups, there was a marked contraction (60% and 67%, respectively) although the periodontal parameters were not affected. The CM group had a significantly lower patient morbidity (pain and medication intake) as well as reduced surgery time.
CONCLUSIONS: These results prove that this new CM was as effective and predictable as the CTG for attaining a band of keratinized tissue, but its use was associated with a significantly lower patient morbidity.
MATERIAL AND METHODS: This randomized longitudinal parallel controlled clinical trial studied 20 patients with at least one location with minimal keratinized tissue (<or=1 mm).
MAIN OUTCOME MEASURE: The 6-month width of keratinized tissue. As secondary outcomes, the aesthetic outlook, the maintenance of periodontal health and the patient morbidity were assessed pre-operatively at 1, 3 and 6 months.
RESULTS: At 6 months, the CTG attained a mean width of keratinized tissue of 2.6 (0.9) mm, while the CM was 2.5 (0.9) mm, these differences being insignificant. In both groups, there was a marked contraction (60% and 67%, respectively) although the periodontal parameters were not affected. The CM group had a significantly lower patient morbidity (pain and medication intake) as well as reduced surgery time.
CONCLUSIONS: These results prove that this new CM was as effective and predictable as the CTG for attaining a band of keratinized tissue, but its use was associated with a significantly lower patient morbidity.
Предметные рубрики MeSH
AdultAgedAnalgesicsBiocompatible MaterialsCollagenConnective TissueDental Prosthesis, Implant-SupportedDenture, Partial, FixedEsthetics, DentalFemaleFollow-Up StudiesGingivaGingival RecessionGingivoplastyHumansKeratinsLongitudinal StudiesMaleMiddle AgedMouth MucosaPostoperative PainPeriodontal Attachment LossPeriodontal IndexPeriodontal PocketProspective StudiesSurgical FlapsTime FactorsTreatment Outcome