[Early diagnosis of Alzheimer disease].

On of the major challenges for public health in developed countries for the 21st century is that of aging, and in particular Alzheimer's disease. Progress has been made in the development of symptomatic treatment and prevention and early diagnosis of Alzheimer's disease is becoming mandatory. In the present state of our knowledge, no marker for early diagnosis has been described. However, the combined use of clinical observations (behavioral and neuropsychological features) and complementary information (brain morphology and functional imaging, biological data, neurophysiology explorations) could be helpful for early diagnosis of Alzheimer's disease well before the onset of dementia.