An international multidisciplinary consensus on pediatric metabolic dysfunction-associated fatty liver disease.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Zhang Le, El-Shabrawi Mortada, Baur Louise A, Byrne Christopher D, Targher Giovanni, Kehar Mohit, Porta Gilda, Lee Way Seah, Lefere Sander, Turan Serap, Alisi Anna, Weiss Ram, Faienza Maria Felicia, Ashraf Ambika, Sundaram Shikha S, Srivastava Anshu, De Bruyne Ruth, Kang Yunkoo, Bacopoulou Flora, Zhou Yong-Hai, Darma Andy, Lupsor-Platon Monica, Hamaguchi Masahide, Misra Anoop, Méndez-Sánchez Nahum, Ng Nicholas Beng Hui, Marcus Claude, Staiano Amanda E, Waheed Nadia, Alqahtani Saleh A, Giannini Cosimo, Ocama Ponsiano, Nguyen Mindie H, Arias-Loste Maria Teresa, Ahmed Mohamed Rabea, Sebastiani Giada, Poovorawan Yong, Al Mahtab Mamun, Pericàs Juan M, Reverbel da Silveira Themis, Hegyi Peter, Azaz Amer, Isa Hasan M, Lertudomphonwanit Chatmanee, Farrag Mona Issa, Nugud Ahmed Abd Alwahab, Du Hong-Wei, Qi Ke-Min, Mouane Nezha, Cheng Xin-Ran, Al Lawati Tawfiq, Fagundes Eleonora D T, Ghazinyan Hasmik, Hadjipanayis Adamos, Fan Jian-Gao, Gimiga Nicoleta, Kamal Naglaa M, Ștefănescu Gabriela, Hong Li, Diaconescu Smaranda, Li Ming, George Jacob, Zheng Ming-Hua
Аннотация
METHODS: A group of 65 experts from 35 countries and six continents, including pediatricians, hepatologists, and endocrinologists, participated in a consensus development process. The process encompassed various aspects of pediatric MAFLD, including epidemiology, mechanisms, screening, and management.
FINDINGS: In round 1, we received 65 surveys from 35 countries and analyzed these results, which informed us that 73.3% of respondents agreed with 20 draft statements while 23.8% agreed somewhat. The mean percentage of agreement or somewhat agreement increased to 80.85% and 15.75%, respectively, in round 2. The final statements covered a wide range of topics related to epidemiology, pathophysiology, and strategies for screening and managing pediatric MAFLD.
CONCLUSIONS: The consensus statements and recommendations developed by an international expert panel serve to optimize clinical outcomes and improve the quality of life for children and adolescents with MAFLD. These findings emphasize the need for standardized approaches in diagnosing and treating pediatric MAFLD.
FUNDING: This work was funded by the National Natural Science Foundation of China (82070588, 82370577), the National Key R&D Program of China (2023YFA1800801), National High Level Hospital Clinical Research Funding (2022-PUMCH-C-014), the Wuxi Taihu Talent Plan (DJTD202106), and the Medical Key Discipline Program of Wuxi Health Commission (ZDXK2021007).