La Revue de medecine interne · 2007
[Pure motor neuropathy, an uncommon complication of radiotherapy: report of 3 cases and review of the literature].
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Mathis S, Dumas P, Neau J-P, Gil R
Аннотация
BACKGROUND: Early or late neurological symptoms with lesions of peripheral or central nervous system can originated from radiotherapy.
METHODS: We report three cases of pure motor neuropathy in patients, which were treated by X-ray treatment several years ago.
RESULTS: Three patients (35-65 years old) have been presenting a pure motor neuropathy between 8.5 and 21 years after radiotherapy for Hodgkin disease (two cases) or testicular seminoma (one case). In each case, a proximodistal weakness with proximal predominance was observed and confirmed by the electromyographic findings. After a gradual worsening, we observed a clinical stability in patients treated by anticoagulant (one case) or pentoxifylline (two cases).
CONCLUSION: Pure motor neuropathy is a rare and late complication of the radiotherapy. A treatment with anticoagulant or pentoxifylline, with or without tocopherol, has been suggested.
METHODS: We report three cases of pure motor neuropathy in patients, which were treated by X-ray treatment several years ago.
RESULTS: Three patients (35-65 years old) have been presenting a pure motor neuropathy between 8.5 and 21 years after radiotherapy for Hodgkin disease (two cases) or testicular seminoma (one case). In each case, a proximodistal weakness with proximal predominance was observed and confirmed by the electromyographic findings. After a gradual worsening, we observed a clinical stability in patients treated by anticoagulant (one case) or pentoxifylline (two cases).
CONCLUSION: Pure motor neuropathy is a rare and late complication of the radiotherapy. A treatment with anticoagulant or pentoxifylline, with or without tocopherol, has been suggested.