[Efficacy of omeprazole in the treatment of Helicobacter pylori-associated duodenal ulcers... in children].

We have observed 25 children: 15 (60%) girls, 10 (40%) boys in age of 11 to 15 y.o. with duodenum ulcer disease. 19 children were found having genealogical ulcer disease. The duration of the disease in the children varied from 6 months to 6 years. The children with long term ulcer disease anamneses have the disease relapse as often as every 4-6 months, 3 children were found with complications of the disease. All children were prescribed omeprazolum along with antibiotics (amoxicillinum, metranidasolum). Omeprazolum was prescribed in doses: 20 mg 2 times per day over 7 days, after it 20 mg 1 time per day over 1 week. The above-mentioned therapy showed good results, ulcer craters have been epithelized in more than a half of the children, in 68% of patients over 14 days. Using of this therapy positively affects the inflammatory and structural changes of gastric mucous coat and the acid level.