[Prokinetic activity and antral inflammation. Usefulness of cisapride combined with H2 antagonists in gastritis].

In order to evaluate the symptomatic efficacy of cisapride on motility disorders often associated with mild inflammatory changes of the upper gastrointestinal tract, the authors carried out a comparison between two groups of patients (15 patients in each group, 10 males and 5 females) with histologic antral gastritis, treated respectively with famotidine 40 mg/day per os plus cisapride 10 mg ter/die per os, and famotidine alone. While the endoscopic evaluation performed four weeks later did not show a significant difference between the two groups, both macroscopically and microscopically, cisapride was able to ameliorate all those symptoms presumably provoked by delayed gastric emptying.